Evaluation of pai-1 polymorphisms in central and peripheral thromboembolies

Thromboembolism is a clinical finding that occurs due to thrombus; formed in the vascular system and has various etiological factors. It can be classified as central peripheral thromboembolism. Our objective this study explore genetic risk factors thromboembolism reveal differences. 342 patients were retrospectively included between January 2016 December 2019. Demographic characteristics, for mutations groups overviewed. The evaluated Factor V Leiden G1691A, HR1299R, II (Prothrombin) G20210A, MTHFR (Methylenetetrahydrofolate reductase) C677T, A1298C, PAI 4G/5G. Within scope of study, analyzes 106 reached study. Seventy-two (69.8%), 34 (31.2%) thromboembolisms detected. Sixty-three from arterial nine venous origin. There was no significant difference age, gender (p˃0.05), but smoking more common (p: 0.041). 4G/5G polymorphism observed frequently with 0.039). multifactorial disease, PAI-1 medium factor We conclude frequent than its evaluation give information about thromboembolic analyze.